• LAB TEST: Comprehensive 9 Female Hormones (Blood)

    by Dr. Clark H. Hansen
    on Jun 1st, 2017

Reasons to take this Test

Menopausal and Perimenopausal Symptoms, Stress, Fatigue, Moodiness, Insomnia, Memory Weakness, Decreased Sexual Desire, Decreased Sexual Stimulation, Thinning and Loss of Pubic Hair, and Hormone Replacement Therapy (HRT) Monitoring.

Product Description

Individual Hormones Tested:

Pregnenolone (P) ($157.50)
Estrone (E1) ($150.93)
Estradiol (E2) ($185.74)
Estriol (E3) ($130.31)
Progesterone (P4) ($139.59)
Dehydroepiandrosterone (DHEA) ($153.41)
Testosterone (T) (195.50)
Sex Hormone Binding Globulin (SHBG) ($150.00)
Free Testosterone (FT) ($25.00)

List Price:  $1285.00

Hansen Clinic 9 Panel Price:  $850  Sale Price $425

The Comprehensive Female 9 Hormone Panel  Blood test is a safe and reliable lab test that measures 9 key hormone levels including Pregnenolone, all three types of Estrogen [Estrone (E1), Estradiol (E2) and Estriol (E3)], Progesterone, DHEA., Testosterone, Sex Hormone Binding Globulin, and Free Testosterone. These hormones are all vital to a woman’s hormonal balance, prevention and treatment of PMS, Endometriosis, Uterine Fibroids, PCOS, Menopause, Low Libido, Obesity, Osteoporosis, Heart Disease and Cancer.

Overview

Hormones exert a powerful influence over a woman’s health. Estrogens give a woman her feminine shape, boost mood and cognitive function, prevent hair loss, thinning of the skin and thinning of the bones. Progesterone calms your mood, improves sleep, builds bone and activates Tumor Suppressor Protein, (p53) helping to prevent cancer. DHEA is an adrenal hormone that regulates cortisol and thyroid hormones, lubricates your joints and helps make Testosterone. Testosterone increases energy, libido, muscle strength and confidence, bone density and prevents brain fog and plaque build-up in the arteries.

A comprehensive assessment of your hormonal balance can be made by measuring Pregnenolone, Estrone, Estradiol, Estriol, DHEA, Progesterone, and Testosterone, SHBG and Free Testosterone. Informed decisions regarding the need to initiate Bio-Identical Hormone Replacement Therapy (BHRT), or how to individualize therapy can then be made to maximize the health benefits of BHRT. Individual differences in hormone metabolism make monitored therapy the best way to prevent cancer and push back the signs of aging.

Careful monitoring and individualization of BHRT can provide women with the benefits of supplemented natural Estrogen while reducing the risk of uterine, ovarian and breast cancer. (An increased cancer risk has been associated with conjugated Estrogen or synthetically modified Estradiol and Progestin hormone use. This is not the case with bio-identical or natural balanced hormone use.)

Pregnenolone

Pregnenolone is the most highly concentrated hormone in the human brain. It is the key hormone that nourishes the brain and protects the nervous system. It is called the “Mother Hormone” because from it all of the other key hormones are derived. Pregnenolone is made in the brain and the adrenal glands from cholesterol and then converted in the liver to DHEA and Progesterone, which then are ultimately converted into all the other key hormones, including Cortisol, Testosterone and the three Estrogens. Beginning at age 35, the body’s natural Pregnenolone levels start to decline. By age 50 they are 50% reduced and by age of 75 the body’s production of this essential brain hormone is almost totally depleted. It’s no wonder we associate memory decline, dementia and Alzheimer’s disease with aging.

Estrogens

A woman’s body produces three different Estrogens, in addition to DHEA, Progesterone and Testosterone which all start from cholesterol produced in the liver. The three types of estrogen are Estrone (E1), Estradiol (E2), and Estriol (E3). Estrone and Estradiol have now been shown to be carcinogenic when given by themselves, while Estriol has been found to be anticarcinogenic and therefore protect the body from the harmful effects of the other two.

However, all of the current estrogen drugs used in this country are combinations of synthetic copies of estrone and estradiol. Rather than admit they were wrong and open themselves up to millions of dollars in law suits, doctors and pharmaceutical companies in the U.S. continue to make the synthetic copies of the forms of estrogen that are known to be carcinogenic, although the safe estrogen, Estriol, has been prescribed in Europe for a number of years.

Doctors and pharmaceutical companies in the U.S. are either afraid to learn the truth and therefore don’t investigate it, or they are involved in a horrible cover-up that is killing thousands of women every year.

Estriol is considered the “forgotten” estrogen. Is has been labeled historically in the US as a weak or ineffective estrogen, while in Europe Estriol has been recognized for its benefits and has been used for years.

Low levels of Estriol place you at an increased risk for developing cancer. You should check all of your Estrogen levels annually to make sure that they are in a healthy balance. You should have 10 times more Estriol than Estradiol and 100 times more Progesterone than Estradiol.

With advancing age, a woman’s ovarian function declines, leading to a decline in the production of Estrogen. This decline leads to vasomotor instability that causes hot flashes. It also causes decreased muscle mass, which is then replaced by fibrous tissue. Thinning skin is due to a loss of connective tissue support and elasticity. Vaginal mucous membranes also become thin and dry and breast tissue diminishes and loses its firmness. Supplementing natural Estriol (E3) and balancing the levels of Estradiol and Estrone can help stop many of these undesirable effects associated with menopause.

Progesterone

Progesterone is mostly produced by the ovaries in women starting from cholesterol. It has its own unique hormonal functions, but a certain amount may also be converted into Estrone. Progesterone increases uterine secretions and stimulates calcium deposits into bone tissue. It also helps regulate salt, control blood sugar, calms the nervous system and promote a healthy thymus gland. Progesterone also activates GABA, the anti-anxiety and deep sleep Neurohormone. Perhaps the most important function of Progesterone is the activation of an anti-cancer protein known as Tumor Suppressor Protein, or p53. Supplementing natural Progesterone can help maintain these healthful benefits. You should have approximately 10 times more Progesterone than Estriol and 100 times more Progesterone than Estradiol for optimal health. You should make sure to check your levels annually.

DHEA

DHEA is the most abundant steroid in the body. DHEA is a steroid precursor produced by the adrenal gland and converted to Testosterone and the Estrogens. DHEA levels decrease dramatically with age. Adequate DHEA levels give the body the building blocks necessary to produce these hormones. Low levels of DHEA are associated with and increase in coronary artery disease, muscle wasting, abdominal fat and osteoporosis. Taking DHEA reverses these processes and may also increase the sense of well-being.

Testosterone

Many women do not know that Testosterone is produced by both men and women. In fact, the steroid hormone Androstenedione is converted in both men and women to Testosterone first, then Testosterone is converted into Estradiol(E2), the major Estrogen secreted by the human ovary. When a woman’s ovarian function declines in the years before and during natural menopause, so does the amount of Testosterone she produces. Between a woman’s 20s and 40s the amount of Testosterone circulating in her blood declines about 50%. If a woman starts synthetic Estrogen Replacement Therapy at menopause, her blood levels of Testosterone drop even further due to a biochemical reaction.

Symptoms such as fatigue, muscle wasting, low sex drive, decreased sexual stimulation, and diminished sense of well-being can be due to a Testosterone deficiency. These symptoms can be significantly improved with natural Testosterone replacement.

Sex Hormone Binding Globulin

SHBG is a protein that binds testosterone and estradiol and transports them in the blood. As a result, the SHBG level affects the amount of these hormones that are available in the body.

SHBG has a high binding affinity to Dihydrotestosterone (DHT), medium affinity to Testosterone and Estradiol, and only a low affinity to Estrone, DHEA, Androstenedione, and Estriol. Elevated SHBG levels can be seen in men and women with high estrogen levels or hyperthyroidism (high thyroid levels) and significant liver disease. SHBG levels also increase when women take oral contraceptives or oral Hormone Replacement Therapy. Pregnant women also have markedly higher SHBG serum concentrations due to their increased estrogen production.

Free Testosterone (Bioavailable Testosterone)

Free Testosterone is the biologically active Testosterone. It provides the best representation of the true functioning level of active Testosterone in the blood stream and its effects on the patient. Free testosterone is also referred to as Bio-Available Testosterone, or the Non-SHBG-bound Testosterone. By calculating the Free Testosterone from the ratio of total testosterone (TT) to SHBG [% FT = (TT / SHBG) x 100], it is possible to calculate the approximate amount of Free Testosterone (FT) that is circulating in the blood stream and available to perform the healthy functions of Testosterone.

 

References

  1. Samsioe G. The endometrium: effects of estrogen and estrogen-progestogen replacement therapy. Int J Fertil Menopausal Stud 1994;39 Suppl 2:84-92
  2. Davis S. Androgen replacement in women: a commentary. J Clin Endocrinol Metab 1999 Jun;84(6):1886-91
  3. Watts NB. Hulka BS. Epidemilogical analysis of breast and gynecological cancers. Prog Clin Biol Res. 1997;396:17-29.
  4. Rosano GM, Panina G. Cardiovascular pharmacology of hormone replacement therapy. Drugs Aging 1999 Sep;15(3):219-34

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Author Dr. Clark H. Hansen Dr. Clark H. Hansen is a licensed Naturopathic Medical Doctor (N.M.D.) who has been in private practice in Scottsdale, Arizona, since 1986. He is the President and Medical Director of the Hansen Clinic of Natural Medicine, Aesthetics and Mesotherapy. Dr. Hansen is one of the most well respected Naturopathic Physicians in the country and a Diplomat of the World Society of Anti-Aging Medicine.

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